Ontology highlight
ABSTRACT:
SUBMITTER: Tang SS
PROVIDER: S-EPMC4909913 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Tang Sai-Sai SS Cheng Jie J Cai Meng-Yun MY Yang Xi-Li XL Liu Xin-Guang XG Zheng Bi-Ying BY Xiong Xing-Dong XD
Disease markers 20160602
lincRNA-p21 plays an important role in the pathogenesis and progression of coronary artery disease (CAD). To date, the biological significance of polymorphisms in lincRNA-p21 on CAD risk remains unknown. Here we aimed to evaluate the influence of lincRNA-p21 polymorphisms on individual susceptibility to CAD. Genotyping of four tagSNPs (rs9380586, rs4713998, rs6930083, and rs6931097) within lincRNA-p21 gene was performed in 615 CAD and 655 controls. The haplotype analysis showed that the haplotyp ...[more]