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Estimating the burden of influenza-associated hospitalizations and deaths in Central America.


ABSTRACT:

Objectives

Our objective was to estimate the incidence of influenza-associated hospitalizations and in-hospital deaths in Central American Region.

Design and setting

We used hospital discharge records, influenza surveillance virology data, and population projections collected from Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua to estimate influenza-associated hospitalizations and in-hospital deaths. We performed a meta-analysis of influenza-associated hospitalizations and in-hospital deaths.

Main outcome measures

The highest annual incidence was observed among children aged <5 years (136 influenza-associated hospitalizations per 100 000 persons).

Results

Annually, 7 625-11 289 influenza-associated hospitalizations and 352-594 deaths occurred in the subregion.

Conclusions

Our results suggest that a substantive number of persons are annually hospitalized because of influenza. Health officials should estimate how many illnesses could be averted through increased influenza vaccination.

SUBMITTER: Descalzo MA 

PROVIDER: S-EPMC4910178 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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<h4>Objectives</h4>Our objective was to estimate the incidence of influenza-associated hospitalizations and in-hospital deaths in Central American Region.<h4>Design and setting</h4>We used hospital discharge records, influenza surveillance virology data, and population projections collected from Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua to estimate influenza-associated hospitalizations and in-hospital deaths. We performed a meta-analysis of influenza-associated hospitalizations  ...[more]

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