Ontology highlight
ABSTRACT:
SUBMITTER: Share AI
PROVIDER: S-EPMC4911636 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Share Andrew I AI Patel Khushali K Nativi Cristina C Cho Eun J EJ Francesconi Oscar O Busschaert Nathalie N Gale Philip A PA Roelens Stefano S Sessler Jonathan L JL
Chemical communications (Cambridge, England) 20160525 48
A series of aminopyrrolic receptors were tested as anion transporters using POPC liposome model membranes. Many were found to be effective Cl(-) transporters and to inhibit clinical strains of Staphylococcus aureus growth in vitro. The best transporters proved effective against the methicillin-resistant Staphylococcus aureus (MRSA) strains, Mu50 and HP1173. Tris-thiourea tren-based chloride transporters were also shown to inhibit the growth of S. aureus in vitro. ...[more]