Reconstruction of Focal Femoral Head Cartilage Defects With a Chitin-Based Scaffold.

ABSTRACT: It is well known that articular cartilage defects have little capability to heal. For grade III or IV cartilage defects, surgical intervention may be required for symptomatic patients. Microfracture is a commonly used surgical technique to address these injuries. However, microfracture has drawbacks, which include the risk of ossification of the newly formed tissue, as well as the imperfect and fragile nature of the fibrous cartilage. Given the challenges associated with microfracture, BST-CarGel (Piramal Healthcare, Laval, Quebec, Canada) has been developed to stabilize and support the nascent clot. This chitin-based polymer is mixed with the patient's own blood and inserted onto the microfractured defect. The polymer allows normal clot formation and provides a matrix to strengthen the clot, prevent retraction, and increase its adhesiveness to the natural tissue. We present, with a video example, a detailed arthroscopic technique for using BST-CarGel to fill a focal femoral head cartilage defect.

SUBMITTER: Al-Qarni A 

PROVIDER: S-EPMC4912569 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature