Ontology highlight
ABSTRACT:
SUBMITTER: Sader HS
PROVIDER: S-EPMC4914695 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20160620 7
A total of 7,272 unique patient clinical isolates were collected from 71 U.S. medical centers from patients with urinary tract infections in 2012 to 2014 and tested for susceptibility to ceftazidime-avibactam and comparators by broth microdilution methods. Ceftazidime-avibactam inhibited >99.9% of all Enterobacteriaceae at the susceptible breakpoint of ≤8 μg/ml (there were only three nonsusceptible strains). Ceftazidime-avibactam was also active against Pseudomonas aeruginosa isolates (MIC50, 2 ...[more]