Ontology highlight
ABSTRACT: Introduction
Achilles tendon (AT) rupture exhibits a prolonged healing process with varying clinical outcome. Reduced blood flow to the AT has been considered an underlying factor to AT rupture (ATR) and impaired healing. In vivo measurements using laser Doppler flowmetry (LDF) may be a viable method to assess blood flow in healthy and healing AT.Methods
29 persons were included in the study; 9 being ATR patients and 20 healthy subjects without any prior symptoms from the AT. Invasive LDF was used to determine the post-occlusive reactive hyperemia (PORH) in the paratenon after 15 minutes of occlusion of the lower extremities. ATR patients were examined two weeks post-operatively.Results
LDF-assessments demonstrated a significantly different (p < 0.001) PORH response in the healing- versus intact- and control AT. In the healing AT, a slow, flattened PORH was observed compared to a fast, high peak PORH in intact, healthy AT.Conclusion
in vivo LDF appears to be a feasible method to assess alterations in blood flow in healing and intact AT. The healing ATs capability to react to an ischemic period is clearly impaired, which may be due to the trauma at injury and/or surgery or degenerative changes in the tendon.
SUBMITTER: Arverud ED
PROVIDER: S-EPMC4915466 | biostudies-literature | 2016 Jan-Mar
REPOSITORIES: biostudies-literature
Arverud Erica Domeij ED Persson-Lindell Olof O Sundquist Fredrik F Labruto Fausto F Edman Gunnar G Ackermann Paul W PW
Muscles, ligaments and tendons journal 20160101 1
<h4>Introduction</h4>Achilles tendon (AT) rupture exhibits a prolonged healing process with varying clinical outcome. Reduced blood flow to the AT has been considered an underlying factor to AT rupture (ATR) and impaired healing. In vivo measurements using laser Doppler flowmetry (LDF) may be a viable method to assess blood flow in healthy and healing AT.<h4>Methods</h4>29 persons were included in the study; 9 being ATR patients and 20 healthy subjects without any prior symptoms from the AT. Inv ...[more]