Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts.
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ABSTRACT:
SUBMITTER: Morse D
PROVIDER: S-EPMC4922565 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts.
Morse David D Webster Wesley W Kalanon Ming M Langsley Gordon G McFadden Geoffrey I GI
PloS one 20160627 6
Over-expression of a GFP-PfRab1A fusion protein in Plasmodium falciparum schizonts produces a punctate pattern of fluorescence typical of rhoptries, secretory organelles involved in host cell invasion. The GFP-positive bodies were purified by a combination of differential and density gradient centrifugation and their protein content determined by MS/MS sequencing. Consistent with the GFP rhoptry-like pattern of transgenic parasites, four of the 19 proteins identified have been previously describ ...[more]
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