Ontology highlight
ABSTRACT:
SUBMITTER: Wekselblatt JB
PROVIDER: S-EPMC4922607 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Wekselblatt Joseph B JB Flister Erik D ED Piscopo Denise M DM Niell Cristopher M CM
Journal of neurophysiology 20160224 6
Sensory-driven behaviors engage a cascade of cortical regions to process sensory input and generate motor output. To investigate the temporal dynamics of neural activity at this global scale, we have improved and integrated tools to perform functional imaging across large areas of cortex using a transgenic mouse expressing the genetically encoded calcium sensor GCaMP6s, together with a head-fixed visual discrimination behavior. This technique allows imaging of activity across the dorsal surface ...[more]