Ontology highlight
ABSTRACT:
SUBMITTER: Yasuda M
PROVIDER: S-EPMC4926057 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Yasuda Masayuki M Tanaka Yuji Y Omodaka Kazuko K Nishiguchi Koji M KM Nakamura Orie O Tsuda Satoru S Nakazawa Toru T
Scientific reports 20160629
Glaucoma is a group of eye diseases characterized by alterations in the contour of the optic nerve head (ONH), with corresponding visual field defects and progressive loss of retinal ganglion cells (RGCs). This progressive RGC death is considered to originate in axonal injury caused by compression of the axon bundles in the ONH. However, the molecular pathomechanisms of axonal injury-induced RGC death are not yet well understood. Here, we used RNA sequencing (RNA-seq) to examine transcriptome ch ...[more]