Unknown

Dataset Information

0

Cancer testis antigen and immunotherapy.


ABSTRACT: The identification of cancer testis (CT) antigens has been an important advance in determining potential targets for cancer immunotherapy. Multiple previous studies have shown that CT antigen vaccines, using both peptides and dendritic cell vaccines, can elicit clinical and immunologic responses in several different tumors. This review details the expression of melanoma antigen family A, 1 (MAGE-A1), melanoma antigen family A, 3 (MAGE-A3), and New York esophageal squamous cell carcinoma-1 (NY-ESO-1) in various malignancies, and presents our current understanding of CT antigen based immunotherapy.

SUBMITTER: Krishnadas DK 

PROVIDER: S-EPMC4928360 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

altmetric image

Publications

Cancer testis antigen and immunotherapy.

Krishnadas Deepa Kolaseri DK   Bai Fanqi F   Lucas Kenneth G KG  

ImmunoTargets and therapy 20130417


The identification of cancer testis (CT) antigens has been an important advance in determining potential targets for cancer immunotherapy. Multiple previous studies have shown that CT antigen vaccines, using both peptides and dendritic cell vaccines, can elicit clinical and immunologic responses in several different tumors. This review details the expression of melanoma antigen family A, 1 (MAGE-A1), melanoma antigen family A, 3 (MAGE-A3), and New York esophageal squamous cell carcinoma-1 (NY-ES  ...[more]

Similar Datasets

| S-EPMC8899981 | biostudies-literature
| S-EPMC5650349 | biostudies-literature
| S-EPMC7102435 | biostudies-literature
| S-EPMC3116976 | biostudies-literature
| S-EPMC4667235 | biostudies-other
| S-EPMC4506364 | biostudies-literature
| S-EPMC4599236 | biostudies-literature
| S-EPMC4458219 | biostudies-literature
| S-EPMC8161805 | biostudies-literature
| S-EPMC8581324 | biostudies-literature