Ontology highlight
ABSTRACT:
SUBMITTER: Mirandola L
PROVIDER: S-EPMC5650349 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Mirandola Leonardo L Pedretti Elisa E Figueroa Jose A JA Chiaramonte Raffaella R Colombo Michela M Chapman Caroline C Grizzi Fabio F Patrinicola Federica F Kast W Martin WM Nguyen Diane D DD Rahman Rakhshanda Layeequr RL Daver Naval N Ruvolo Peter P Post Sean M SM Bresalier Robert S RS Chiriva-Internati Maurizio M
Oncotarget 20170810 43
Breast carcinoma is a major health issue for millions of women. Current therapies have serious side effects, and are only partially effective in patients with metastatic tumors. Thus, the need for novel and less toxic therapies is urgent. Moreover, hormonal and antibody therapies effective in other subtypes are not effective in Triple Negative Breast Cancer (TNBC). Immunotherapeutic strategies directed against specific tumor-associated antigens (TAAs) and mediated by specific cytotoxic T lymphoc ...[more]