Ontology highlight
ABSTRACT:
SUBMITTER: Aagaard K
PROVIDER: S-EPMC4929217 | biostudies-literature | 2014 May
REPOSITORIES: biostudies-literature
Aagaard Kjersti K Ma Jun J Antony Kathleen M KM Ganu Radhika R Petrosino Joseph J Versalovic James J
Science translational medicine 20140501 237
Humans and their microbiomes have coevolved as a physiologic community composed of distinct body site niches with metabolic and antigenic diversity. The placental microbiome has not been robustly interrogated, despite recent demonstrations of intracellular bacteria with diverse metabolic and immune regulatory functions. A population-based cohort of placental specimens collected under sterile conditions from 320 subjects with extensive clinical data was established for comparative 16S ribosomal D ...[more]