Plasma concentrations of coffee polyphenols and plasma biomarkers of diabetes risk in healthy Japanese women.

ABSTRACT: Coffee consumption has been reported to reduce the risk of type 2 diabetes in experimental and epidemiological studies. This anti-diabetic effect of coffee may be attributed to its high content in polyphenols especially caffeic acid and chlorogenic acid. However, the association between plasma coffee polyphenols and diabetic risks has never been investigated in the literature. In this study, fasting plasma samples were collected from 57 generally healthy females aged 38-73 (mean 52, s.d. 8) years recruited in Himeji, Japan. The concentrations of plasma coffee polyphenols were determined by liquid chromatography coupled with mass tandem spectrometer. Diabetes biomarkers in the plasma/serum samples were analysed by a commercial diagnostic laboratory. Statistical associations were assessed us

SUBMITTER: Lee AH 

PROVIDER: S-EPMC4931312 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature