Ontology highlight
ABSTRACT:
SUBMITTER: Groeme R
PROVIDER: S-EPMC4933224 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Groeme Rachel R Airouche Sabi S Kopečný David D Jaekel Judith J Savko Martin M Berjont Nathalie N Bussieres Laetitia L Le Mignon Maxime M Jagic Franck F Zieglmayer Petra P Baron-Bodo Véronique V Bordas-Le Floch Véronique V Mascarell Laurent L Briozzo Pierre P Moingeon Philippe P
The Journal of biological chemistry 20160419 25
Allergy to the short ragweed (Ambrosia artemisiifolia) pollen is a major health problem. The ragweed allergen repertoire has been recently expanded with the identification of Amb a 11, a new major allergen belonging to the cysteine protease family. To better characterize Amb a 11, a recombinant proform of the molecule with a preserved active site was produced in Escherichia coli, refolded, and processed in vitro into a mature enzyme. The enzymatic activity is revealed by maturation following an ...[more]