Ontology highlight
ABSTRACT:
SUBMITTER: Ashauer R
PROVIDER: S-EPMC4933929 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Ashauer Roman R Albert Carlo C Augustine Starrlight S Cedergreen Nina N Charles Sandrine S Ducrot Virginie V Focks Andreas A Gabsi Faten F Gergs André A Goussen Benoit B Jager Tjalling T Kramer Nynke I NI Nyman Anna-Maija AM Poulsen Veronique V Reichenberger Stefan S Schäfer Ralf B RB Van den Brink Paul J PJ Veltman Karin K Vogel Sören S Zimmer Elke I EI Preuss Thomas G TG
Scientific reports 20160706
The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test the ability of GUTS to predict survival of aquatic organisms across different pesticide exposure patterns, time scales and species. Firstly, using synthetic data, we identified experimental data requirements whi ...[more]