Role of bile acids in the regulation of the metabolic pathways.
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ABSTRACT:
SUBMITTER: Taoka H
PROVIDER: S-EPMC4937164 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Publications
Role of bile acids in the regulation of the metabolic pathways.
Taoka Hiroki H Yokoyama Yoko Y Morimoto Kohkichi K Kitamura Naho N Tanigaki Tatsuya T Takashina Yoko Y Tsubota Kazuo K Watanabe Mitsuhiro M
World journal of diabetes 20160701 13
Recent studies have revealed that bile acids (BAs) are not only facilitators of dietary lipid absorption but also important signaling molecules exerting multiple physiological functions. Some major signaling pathways involving the nuclear BAs receptor farnesoid X receptor and the G protein-coupled BAs receptor TGR5/M-BAR have been identified to be the targets of BAs. BAs regulate their own homeostasis via signaling pathways. BAs also affect diverse metabolic pathways including glucose metabolism ...[more]
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