Ontology highlight
ABSTRACT:
SUBMITTER: Dunn KE
PROVIDER: S-EPMC4937388 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20160708
Surface-immobilization of molecules can have a profound influence on their structure, function and dynamics. Toehold-mediated strand displacement is often used in solution to drive synthetic nanomachines made from DNA, but the effects of surface-immobilization on the mechanism and kinetics of this reaction have not yet been fully elucidated. Here we show that the kinetics of strand displacement in surface-immobilized nanomachines are significantly different to those of the solution phase reactio ...[more]