Ontology highlight
ABSTRACT:
SUBMITTER: Tamada M
PROVIDER: S-EPMC4939091 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Tamada Masako M Zallen Jennifer A JA
Developmental cell 20151001 2
Cells display dynamic and diverse morphologies during development, but the strategies by which differentiated tissues achieve precise shapes and patterns are not well understood. Here we identify a developmental program that generates a highly ordered square cell grid in the Drosophila embryo through sequential and spatially regulated cell alignment, oriented cell division, and apicobasal cell elongation. The basic leucine zipper transcriptional regulator Cnc is necessary and sufficient to produ ...[more]