Ontology highlight
ABSTRACT:
SUBMITTER: Dubois NC
PROVIDER: S-EPMC4949030 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Dubois Nicole C NC Craft April M AM Sharma Parveen P Elliott David A DA Stanley Edouard G EG Elefanty Andrew G AG Gramolini Anthony A Keller Gordon G
Nature biotechnology 20111023 11
To identify cell-surface markers specific to human cardiomyocytes, we screened cardiovascular cell populations derived from human embryonic stem cells (hESCs) against a panel of 370 known CD antibodies. This screen identified the signal-regulatory protein alpha (SIRPA) as a marker expressed specifically on cardiomyocytes derived from hESCs and human induced pluripotent stem cells (hiPSCs), and PECAM, THY1, PDGFRB and ITGA1 as markers of the nonmyocyte population. Cell sorting with an antibody ag ...[more]