Ontology highlight
ABSTRACT:
SUBMITTER: Mitchell JA
PROVIDER: S-EPMC4954586 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Mitchell Jonathan A JA Cousminer Diana L DL Zemel Babette S BS Grant Struan F A SF Chesi Alessandra A
BoneKEy reports 20160720
Osteoporosis is one of the most common chronic forms of disability in postmenopausal women and represents a major health burden around the world. Bone fragility is affected by bone mineral density (BMD), and, one of the most important factors in preventing osteoporosis is optimizing peak bone mass, which is achieved during growth in childhood and adolescence. BMD is a complex trait resulting from environmental and genetic factors. Genome-wide association studies have discovered robust genetic si ...[more]