Free energy cost of reducing noise while maintaining a high sensitivity.
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ABSTRACT:
SUBMITTER: Sartori P
PROVIDER: S-EPMC4955832 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Publications
Free energy cost of reducing noise while maintaining a high sensitivity.
Physical review letters 20150908 11
Living systems need to be highly responsive, and also to keep fluctuations low. These goals are incompatible in equilibrium systems due to the fluctuation dissipation theorem (FDT). Here, we show that biological sensory systems, driven far from equilibrium by free energy consumption, can reduce their intrinsic fluctuations while maintaining high responsiveness. By developing a continuum theory of the E. coli chemotaxis pathway, we demonstrate that adaptation can be understood as a nonequilibrium ...[more]
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