Ontology highlight
ABSTRACT:
SUBMITTER: Anantpadma M
PROVIDER: S-EPMC4958205 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Anantpadma Manu M Kouznetsova Jennifer J Wang Hang H Huang Ruili R Kolokoltsov Andrey A Guha Rajarshi R Lindstrom Aaron R AR Shtanko Olena O Simeonov Anton A Maloney David J DJ Maury Wendy W LaCount Douglas J DJ Jadhav Ajit A Davey Robert A RA
Antimicrobial agents and chemotherapy 20160722 8
Filoviruses are highly infectious, and no FDA-approved drug therapy for filovirus infection is available. Most work to find a treatment has involved only a few strains of Ebola virus and testing of relatively small drug libraries or compounds that have shown efficacy against other virus types. Here we report the findings of a high-throughput screening of 319,855 small molecules from the Molecular Libraries Small Molecule Repository library for their activities against Marburg virus and Ebola vir ...[more]