Ontology highlight
ABSTRACT:
SUBMITTER: Vornanen M
PROVIDER: S-EPMC4960994 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Vornanen Matti M Hassinen Minna M
Channels (Austin, Tex.) 20151215 2
The zebrafish (Danio rerio) has become a popular model for human cardiac diseases and pharmacology including cardiac arrhythmias and its electrophysiological basis. Notably, the phenotype of zebrafish cardiac action potential is similar to the human cardiac action potential in that both have a long plateau phase. Also the major inward and outward current systems are qualitatively similar in zebrafish and human hearts. However, there are also significant differences in ionic current composition b ...[more]