Ontology highlight
ABSTRACT:
SUBMITTER: Osborne CA
PROVIDER: S-EPMC4962794 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Organic letters 20151027 21
The enantioselective silver-catalyzed propargylation of N-sulfonylketimines is described. This reaction proceeds in high yield and excellent enantiomeric ratio and is compatible with a wide variety of diaryl- and alkylketimines. Synthetic transformations of homopropargylic products via enyne ring-closing metathesis, Sonogashira cross-coupling, and reduction reactions proceed with high stereochemical fidelity. Both allenyl and propargyl borolane reagents can be used to obtain homopropargylic prod ...[more]