Ontology highlight
ABSTRACT:
SUBMITTER: Wang A
PROVIDER: S-EPMC4969083 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Wang Andrew A Vijayraghavan Karthik K Solgaard Olav O Butte Manish J MJ
ACS nano 20151215 1
The cytoskeleton controls cellular morphology and mediates the mechanical interactions between a cell and its environment. Atomic force microscopy (AFM) has the unique capability to map cytoskeletal mechanics and structures with nanometer resolution. However, whole-cell cytomechanical imaging with conventional AFM techniques is limited by low imaging speed. Here, we present fast nanomechanical mapping of cells using high-bandwidth AFM (HB-AFM), where >10(6) nanoindentation measurements were acqu ...[more]