Ontology highlight
ABSTRACT:
SUBMITTER: Mulligan N
PROVIDER: S-EPMC4972814 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Mulligan Nikki N Schalkwijk Stein S Best Brookie M BM Colbers Angela A Wang Jiajia J Capparelli Edmund V EV Moltó José J Stek Alice M AM Taylor Graham G Smith Elizabeth E Hidalgo Tenorio Carmen C Chakhtoura Nahida N van Kasteren Marjo M Fletcher Courtney V CV Mirochnick Mark M Burger David D
Frontiers in pharmacology 20160804
<h4>Background</h4>The study goal was to describe etravirine pharmacokinetics during pregnancy and postpartum in HIV-infected women.<h4>Methods</h4>IMPAACT P1026s and PANNA are on-going, non-randomized, open-label, parallel-group, multi-center phase-IV prospective studies in HIV-infected pregnant women. Intensive steady-state 12-h pharmacokinetic profiles were performed from 2nd trimester through postpartum. Etravirine was measured at two labs using validated ultra performance liquid chromatogra ...[more]