Ontology highlight
ABSTRACT:
SUBMITTER: Miyamoto K
PROVIDER: S-EPMC4973152 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Miyamoto K K Seki N N Matsushita R R Yonemori M M Yoshino H H Nakagawa M M Enokida H H
British journal of cancer 20160616 3
<h4>Background</h4>Previous studies have revealed that miR-26a-5p and miR-26b-5p act as tumour suppressors in various types of cancer tissues. Here, we aimed to investigate the functional roles of these miRNAs and to identify their regulatory targets in bladder cancer (BC).<h4>Methods</h4>We performed functional assays in BC cells using transfection of mature microRNAs (miRNAs). In silico and luciferase reporter analyses were applied to identify target genes of these miRNAs. The overall survival ...[more]