Ontology highlight
ABSTRACT:
SUBMITTER: Dai Y
PROVIDER: S-EPMC4974504 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Dai Yawei Y Seeger Markus M Weng Jingwei J Song Song S Wang Wenning W Tan Yan-Wen YW
Scientific reports 20160805
Cellular informational and metabolic processes are propagated with specific membrane fusions governed by soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNARE). SNARE protein Ykt6 is highly expressed in brain neurons and plays a critical role in the membrane-trafficking process. Studies suggested that Ykt6 undergoes a conformational change at the interface between its longin domain and the SNARE core. In this work, we study the conformational state distributions and dynam ...[more]