Ontology highlight
ABSTRACT:
SUBMITTER: Perez-Sanchez C
PROVIDER: S-EPMC4977549 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Pérez-Sánchez C C Aguirre M A MA Ruiz-Limón P P Barbarroja N N Jiménez-Gómez Y Y de la Rosa I Arias IA Rodriguez-Ariza A A Collantes-Estévez E E Segui P P Velasco F F Cuadrado M J MJ Teruel R R González-Conejero R R Martínez C C López-Pedrera Ch Ch
Scientific reports 20160809
MicroRNAs markedly affect the immune system, and have a relevant role in CVD and autoimmune diseases. Yet, no study has analyzed their involvement in atherothrombosis related to APS and SLE patients. This study intended to: 1) identify and characterize microRNAs linked to CVD in APS and SLE; 2) assess the effects of specific autoantibodies. Six microRNAs, involved in atherothrombosis development, were quantified in purified leukocytes from 23 APS and 64 SLE patients, and 56 healthy donors. Level ...[more]