Ontology highlight
ABSTRACT:
SUBMITTER: Naimark DM
PROVIDER: S-EPMC4978054 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Naimark David M J DM Grams Morgan E ME Matsushita Kunihiro K Black Corri C Drion Iefke I Fox Caroline S CS Inker Lesley A LA Ishani Areef A Jee Sun Ha SH Kitamura Akihiko A Lea Janice P JP Nally Joseph J Peralta Carmen Alicia CA Rothenbacher Dietrich D Ryu Seungho S Tonelli Marcello M Yatsuya Hiroshi H Coresh Josef J Gansevoort Ron T RT Warnock David G DG Woodward Mark M de Jong Paul E PE
Journal of the American Society of Nephrology : JASN 20151211 8
A single determination of eGFR associates with subsequent mortality risk. Prior decline in eGFR indicates loss of kidney function, but the relationship to mortality risk is uncertain. We conducted an individual-level meta-analysis of the risk of mortality associated with antecedent eGFR slope, adjusting for established risk factors, including last eGFR, among 1.2 million subjects from 12 CKD and 22 other cohorts within the CKD Prognosis Consortium. Over a 3-year antecedent period, 12% of partici ...[more]