Ontology highlight
ABSTRACT:
SUBMITTER: Zhuang H
PROVIDER: S-EPMC4979463 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhuang H H Hu D D Singer D D Walker J V JV Nisr R B RB Tieu K K Ali K K Tredwin C C Luo S S Ardu S S Hu B B
Cell death discovery 20150907
Pulp cells are essential for tooth development, and dentin repair and regeneration. In addition these cells have been identified as an important stem cell source. Local anesthetics are widely used in dental clinics, as well as the other clinical disciplines and have been suggested to interfere with human permanent tooth development and induce tooth agenesis through unknown mechanisms. Using pig model and human young permanent tooth pulp cells, our research has identified that the local anestheti ...[more]