Transcriptomics

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Gene expression profiling in murine mesenchymal stem cells treated with local anesthetics (ropivacaine)


ABSTRACT: Mesenchymal stem cells (MSCs) are recruited from the blood stream to tumors, healing wounds or sites of tissue injury by multiple growth factors and chemokines where they differentiate into e.g. fibroblasts or endothelial cells. Engrafted at the sites of tissue damage, they secrete growth factors and cytokines that facilitate healing. Inhibition of MSC proliferation by prolonged application of local anesthetics (commonly used after surgery) could delay wound closure and promote wound dehiscence.

ORGANISM(S): Mus musculus

PROVIDER: GSE31827 | GEO | 2012/08/31

SECONDARY ACCESSION(S): PRJNA145125

REPOSITORIES: GEO

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