Ontology highlight
ABSTRACT:
SUBMITTER: Ma C
PROVIDER: S-EPMC4979814 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Ma Chong C Gu Liyan L Yang Mingyuan M Zhang Zhensheng Z Zeng Shuxiong S Song Ruixiang R Xu Chuanliang C Sun Yinghao Y
Medicine 20160801 31
Rs1495741 has been identified to infer N-acetyltransferase 2 (NAT2) acetylator phenotype, and to decrease the risk of bladder cancer. However, a number of studies conducted in various regions showed controversial results. To quantify the association between rs1495741 and the risk of bladder cancer and to estimate the interaction effect of this genetic variant with smoking, we performed a systematic literature review and meta-analysis involving 14,815 cases and 58,282 controls from 29 studies. Ou ...[more]