Microinfarcts are common and strongly related to dementia in the oldest-old: The 90+ study.
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ABSTRACT:
SUBMITTER: Corrada MM
PROVIDER: S-EPMC4980175 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Microinfarcts are common and strongly related to dementia in the oldest-old: The 90+ study.
Corrada María M MM Sonnen Joshua A JA Kim Ronald C RC Kawas Claudia H CH
Alzheimer's & dementia : the journal of the Alzheimer's Association 20160528 8
<h4>Introduction</h4>We estimated the prevalence of microinfarcts and their association with dementia in a cohort of oldest-old participants.<h4>Methods</h4>Participants were from The 90+ Study, a population-based study of people 90 years and older. Dementia diagnoses were assigned postmortem during a consensus conference. Microinfarcts were evaluated in six brain regions.<h4>Results</h4>At death, the 213 participants were on average 97 years old, 69% were women, and 52% had dementia. Of the par ...[more]
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