Ontology highlight
ABSTRACT:
SUBMITTER: Budzko L
PROVIDER: S-EPMC4980658 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Budzko Lucyna L Marcinkowska-Swojak Malgorzata M Jackowiak Paulina P Kozlowski Piotr P Figlerowicz Marek M
Scientific reports 20160811
Copy number variation (CNV) is a newly discovered form of intra-species genetic polymorphism that is defined as deletions or duplications of genome segments ranging from 1 kbp to several Mbp. CNV accounts for the majority of the genetic variation observed in humans (CNV regions cover more than 10% of the human genome); therefore, it may significantly influence both the phenotype and susceptibility to various diseases. Unfortunately, the impact of CNV on a number of diseases, including hepatitis ...[more]