Can a central blood volume deficit be detected by systolic pressure variation during spontaneous breathing?
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ABSTRACT:
SUBMITTER: Dahl M
PROVIDER: S-EPMC4982018 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
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Can a central blood volume deficit be detected by systolic pressure variation during spontaneous breathing?
Dahl Michael M Hayes Chris C Steen Rasmussen Bodil B Larsson Anders A Secher Niels H NH
BMC anesthesiology 20160811 1
<h4>Background</h4>Whether during spontaneous breathing arterial pressure variations (APV) can detect a volume deficit is not established. We hypothesized that amplification of intra-thoracic pressure oscillations by breathing through resistors would enhance APV to allow identification of a reduced cardiac output (CO). This study tested that hypothesis in healthy volunteers exposed to central hypovolemia by head-up tilt.<h4>Methods</h4>Thirteen healthy volunteers were exposed to central hypovole ...[more]
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