Ontology highlight
ABSTRACT:
SUBMITTER: Robinson MR
PROVIDER: S-EPMC4984852 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Nature genetics 20150914 11
Across-nation differences in the mean values for complex traits are common, but the reasons for these differences are unknown. Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries. Using discovery data on over 250,000 individuals and unbiased effect size estimates from 17,500 sibling pairs, we estimate that 24% (95% credible interval (CI) = 9%, 41%) and 8% (95% CI = 4%, 16%) of t ...[more]