Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC7933291 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Guo Jing J Bakshi Andrew A Wang Ying Y Jiang Longda L Yengo Loic L Goddard Michael E ME Visscher Peter M PM Yang Jian J
Scientific reports 20210304 1
Genome-wide association studies (GWAS) in samples of European ancestry have identified thousands of genetic variants associated with complex traits in humans. However, it remains largely unclear whether these associations can be used in non-European populations. Here, we seek to quantify the proportion of genetic variation for a complex trait shared between continental populations. We estimated the between-population correlation of genetic effects at all SNPs ([Formula: see text]) or genome-wide ...[more]