Ontology highlight
ABSTRACT:
SUBMITTER: Barbour A
PROVIDER: S-EPMC4985645 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Barbour Abdelahhad A Tagg John J Abou-Zied Osama K OK Philip Koshy K
Scientific reports 20160816
Salivaricin B is a 25 amino acid polycyclic peptide belonging to the type AII lantibiotics and first shown to be produced by Streptococcus salivarius. In this study we describe the bactericidal mode of action of salivaricin B against susceptible Gram-positive bacteria. The killing action of salivaricin B required micro-molar concentrations of lantibiotic whereas the prototype lantibiotic nisin A was shown to be potent at nano-molar levels. Unlike nisin A, salivaricin B did not induce pore format ...[more]