The Sleep/Wake Cycle is Directly Modulated by Changes in Energy Balance.

ABSTRACT:

Study objectives

The rise in obesity has been paralleled by a decline in sleep duration in epidemiological studies. However, the potential mechanisms linking energy balance and the sleep/wake cycle are not well understood. We aimed to examine the effects of manipulating energy balance on the sleep/wake cycle.

Methods

Twelve healthy normal weight men were housed in a clinical research facility and studied at three time points: baseline, after energy balance was disrupted by 2 days of caloric restriction to 10% of energy requirements, and after energy balance was restored by 2 days of ad libitum/free feeding. Sleep architecture, duration of sleep stages, and sleep-associated respiratory parameters were measured by polysomnography.

Results

Two days of caloric restriction

SUBMITTER: Collet TH 

PROVIDER: S-EPMC4989258 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature