Ontology highlight
ABSTRACT:
SUBMITTER: Nayar S
PROVIDER: S-EPMC4991245 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Nayar Saba S Campos Joana J Chung Ming May MM Navarro-Núñez Leyre L Chachlani Menka M Steinthal Nathalie N Gardner David H DH Rankin Philip P Cloake Thomas T Caamaño Jorge H JH McGettrick Helen M HM Watson Steve P SP Luther Sanjiv S Buckley Christopher D CD Barone Francesca F
Journal of immunology (Baltimore, Md. : 1950) 20160729 5
Lymphangiogenesis associated with tertiary lymphoid structure (TLS) has been reported in numerous studies. However, the kinetics and dynamic changes occurring to the lymphatic vascular network during TLS development have not been studied. Using a viral-induced, resolving model of TLS formation in the salivary glands of adult mice we demonstrate that the expansion of the lymphatic vascular network is tightly regulated. Lymphatic vessel expansion occurs in two distinct phases. The first wave of ex ...[more]