Ontology highlight
ABSTRACT:
SUBMITTER: Zhou Q
PROVIDER: S-EPMC4991428 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Zhou Quan Q Chen Fengli F Fei Zhongting Z Zhao Jiali J Liang Yong Y Pan Wei W Liu Xingxiang X Zheng Donghui D
Oncotarget 20160401 15
Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents and young adults. However, the essential mechanisms underlying osteosarcomagenesis remain obscure. The HOTAIR, a well-known long noncoding RNA (lncRNA), is involved in pathogenesis and progress of multiple tumors. To reveal the potential role of lncRNA HOTAIR in OS carcinogenesis, we conducted a two-stage, case-control study among Chinese population with 900 OS cases and 900 controls to evaluated associations of its ...[more]