Ontology highlight
ABSTRACT:
SUBMITTER: Danchin A
PROVIDER: S-EPMC4993169 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Microbial biotechnology 20160720 5
The experimental design of a minimal synthetic genome revealed the presence of a large number of genes without ascribed function, in part because the abstract laws of life must be implemented within ad hoc material contraptions. Creating a function needs recruitment of some pre-existing structure and this reveals kludges in their set-up and history. Here, we show that looking for functions as an engineer would help in discovery of a significant number of those, proposed together with conceptual ...[more]