Ontology highlight
ABSTRACT:
SUBMITTER: Santos LS
PROVIDER: S-EPMC6722859 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Santos Luís S LS Gomes Bruno Costa BC Bastos Hélder N HN Gil Octávia M OM Azevedo Ana Paula AP Ferreira Teresa C TC Limbert Edward E Silva Susana N SN Rueff José J
Genes 20190801 8
The incidence of thyroid cancer (TC), particularly well-differentiated forms (DTC), has been rising and remains the highest among endocrine malignancies. Although ionizing radiation (IR) is well established on DTC aetiology, other environmental and genetic factors may also be involved. DNA repair single nucleotide polymorphisms (SNPs) could be among the former, helping in explaining the high incidence. To further clarify the role of DNA repair SNPs in DTC susceptibility, we analyzed 36 SNPs in 2 ...[more]