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Diabetes mellitus in Zambia and the Western Cape province of South Africa: Prevalence, risk factors, diagnosis and management.


ABSTRACT:

Aims

To determine the prevalence of and risk factors for diabetes mellitus and examine its diagnosis and management in the study communities.

Methods

This is a population-based cross-sectional study among adults in 24 communities from Zambia and the Western Cape (WC) province of South Africa. Diabetes is defined as a random blood glucose concentration (RBG)?11.1mmol/L, or RBG<11.1mmol/L but with a self-reported prior diabetes diagnosis. For individuals with a prior diagnosis of diabetes, RBG<7.8mmol/L was considered to be an acceptable level of glycaemia.

Results

Among 45,767 Zambian and 12,496 WC participants the age-standardised prevalence of diabetes was 3.5% and 7.2% respectively. The highest risk groups identified were those of older age and those with obesity. Of those identified to have diabetes, 34.5% in Zambia and 12.7% in WC were previously unaware of their diagnosis. Among Zambian participants with diabetes, this proportion was lower among individuals with better education or with higher household socio-economic position. Of all those with previously diagnosed diabetes, 66.0% in Zambia and 59.4% in WC were not on any diabetes treatment, and 34.4% in Zambia and 32.7% in WC had a RBG concentration beyond the recommended level, ?7.8mmol/L.

Conclusions

The diabetes risk factor profile for our study communities is similar to that seen in high-income populations. A high proportion of individuals with diabetes are not on diabetes treatment and of those on treatment a high proportion have high glycaemic concentrations. Such data may assist in healthcare planning to ensure timely diagnosis and management of diabetes.

SUBMITTER: Bailey SL 

PROVIDER: S-EPMC4994576 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature

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Publications

Diabetes mellitus in Zambia and the Western Cape province of South Africa: Prevalence, risk factors, diagnosis and management.

Bailey Sarah Lou SL   Ayles Helen H   Beyers Nulda N   Godfrey-Faussett Peter P   Muyoyeta Monde M   du Toit Elizabeth E   Yudkin John S JS   Floyd Sian S  

Diabetes research and clinical practice 20160507


<h4>Aims</h4>To determine the prevalence of and risk factors for diabetes mellitus and examine its diagnosis and management in the study communities.<h4>Methods</h4>This is a population-based cross-sectional study among adults in 24 communities from Zambia and the Western Cape (WC) province of South Africa. Diabetes is defined as a random blood glucose concentration (RBG)⩾11.1mmol/L, or RBG<11.1mmol/L but with a self-reported prior diabetes diagnosis. For individuals with a prior diagnosis of di  ...[more]

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