Ontology highlight
ABSTRACT:
SUBMITTER: Heitz DR
PROVIDER: S-EPMC4994715 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20160623 16
Iridium- and ruthenium-free approaches to protected allylic amines and alkyl nitriles under photoredox conditions are reported. An inexpensive organic dye, eosin Y, catalyzes coupling of Boc-protected potassium α-aminomethyltrifluoroborates with a variety of substituted alkenyl sulfones through an α-aminomethyl radical addition-elimination pathway. Allylic and homoallylic amines were formed in moderate yields with high E/Z selectivity. The mechanistic approach was extended using tosyl cyanide as ...[more]