Ontology highlight
ABSTRACT:
SUBMITTER: Jonas RK
PROVIDER: S-EPMC4996003 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Jonas Rachel K RK Jalbrzikowski Maria M Montojo Caroline A CA Patel Arati A Kushan Leila L Chow Carolyn C CC Vesagas Therese T Bearden Carrie E CE
Molecular neuropsychiatry 20151204 4
22q11.2 deletion syndrome (22q11DS) is a neurogenetic disorder associated with elevated rates of developmental neuropsychiatric disorders and impaired executive function (EF). Disrupted brain structure-function relationships may underlie EF deficits in 22q11DS. We administered the Behavior Rating Inventory of Executive Function (BRIEF) to assess real-world EF in patients with 22q11DS and matched controls (n = 86; age 6-17 years), along with cognitive measures that tap behavioral regulation and m ...[more]