Current Trends in Identifying Rapidly Acting Treatments for Depression.
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ABSTRACT:
SUBMITTER: Ionescu DF
PROVIDER: S-EPMC5001565 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Current Trends in Identifying Rapidly Acting Treatments for Depression.
Ionescu Dawn F DF Papakostas George I GI
Current behavioral neuroscience reports 20160415 2
Traditional antidepressant medications generally take weeks-to-months to achieve effect. However, the breakthrough finding of ketamine's rapidly acting antidepressant properties has inspired a decade-and-a-half of progress towards the identification of treatments that work quickly-within hours-to-days. This paradigm-shift in the discovery of antidepressant therapies has significantly changed the current landscape of antidepressant drug development. Building on this, the current review briefly hi ...[more]
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