Ontology highlight
ABSTRACT:
SUBMITTER: Bird JG
PROVIDER: S-EPMC5001585 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Nucleic acids research 20160420 14
The Escherichia coli σ70 initiation factor is required for a post-initiation, promoter-proximal pause essential for regulation of lambdoid phage late gene expression; potentially, σ70 acts at other sites during transcription elongation as well. The pause is induced by σ70 binding to a repeat of the promoter -10 sequence. After σ70 binding, further RNA synthesis occurs as DNA is drawn (or 'scrunched') into the enzyme complex, presumably exactly as occurs during initial synthesis from the promoter ...[more]