Ontology highlight
ABSTRACT:
SUBMITTER: Ghosh S
PROVIDER: S-EPMC5007645 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Ghosh Sourish S Mukherjee Sriparna S Sengupta Nabonita N Roy Arunava A Dey Dhritiman D Chakraborty Surajit S Chattopadhyay Dhrubajyoti D Banerjee Arpan A Basu Anirban A
Scientific reports 20160901
Network analysis through graph theory provides a quantitative approach to characterize specific proteins and their constituent assemblies that underlie host-pathogen interactions. In the present study, graph theory was used to analyze the interactome designed out of 50 differentially expressing proteins from proteomic analysis of Chandipura Virus (CHPV, Family: Rhabdoviridae) infected mouse brain tissue to identify the primary candidates for intervention. Using the measure of degree centrality, ...[more]